Tuesday, March 14, 2017
New York Times (Feb. 15, 2017): Human Gene Editing Receives Key Panel's Support, by Amy Harmon:
In a move that some fear heralds the era of designer babies for the very wealthy and that has led other countries to ban germ line genetic editing, a panel of influential American scientists has thrown its support behind inheritable modifications of human embryos. Although touted as a way to cure disease, many see the potential for this science to be used for more nefarious motives--enhancing mental or physical endowments, for example--that smack of eugenics.
The research is explicitly aimed at allowing parents who both carry deadly recessive traits to have children who are not afflicted by such diseases as Tay-Sachs, beta thalassemia, and Huntington's. The report calls for prohibitions on using the technology for enhancements, but it does not have any legal effect. Federal law, though, currently prohibits the use of "federal money to support research that results in genetically modified offspring."
The issue arises on the heels of technology--Crispr-Cas9--that brings germ-line genetic editing out of the realm of science fiction. The tool allows researchers to insert and delete genes more or less precisely, although the possibility remains that some DNA will be snipped off inadvertently. They will experiment first on patients with cancer and blindness using genetic alterations that are not inheritable.
Friday, July 15, 2016
New York Magazine (July 7, 2016): Why Do We Treat Sexually Abusive Doctors Differently Than Other Predators?, by Susan Rinkunas
Linking to a study done by the Atlanta Journal Constitution, this article and the study explores the safe space that doctors create with patients, and the physicians that violate that safe space with unwarranted sexual harassment or assault. For many women seeking reproductive - or other types of - healthcare, it is more confusing when doctors cross a line because of the power they hold, the space they share with patients, and the inherent vulnerability of being in an exam room with someone who has vowed to "do no harm." The medical profession also seems to look the other way when when people are courageous enough to step forward and report these offenders:
Medical boards do publicly reprimand doctors, with sanctions including treatment programs, required chaperones when seeing female patients, and monitoring of their practice. Still, the reporters found that, of 2,400 doctors publicly disciplined for sexual misconduct nationwide since 1999, half still had active medical licenses. Some doctors who lost their licenses simply applied for one in another state.
The report raises the question: Why are some doctors seemingly given a pass while abusive coaches, teachers, and, more recently, priests get registered as sex offenders?
Tuesday, October 20, 2015
New York Times (Oct. 16, 2015): Egg Donors Challenge Pay Rates, by Tamar Lewin:
In a federal lawsuit, a group of women are challenging [infertility] industry guidelines that say it is “inappropriate” to pay a woman more than $10,000 for her eggs. The women say the $10,000 limit amounts to illegal price-fixing, and point out that there is no price restriction on the sale of human sperm. A federal judge has certified the claim as a class action.
The crux of the lawsuit is the allegation that infertility clinics have set the price of egg donor services at a low, non-competitive level, in a move that draws infertile couples to infertility clinics. The industry has responded that the guideline aims to protect egg donors and recipients, an arguably procompetitive motive. But as Kimberly Krawiec has pointed out, the evidence in the case seems to point the other way: egg donors could command higher prices in the open market. A cap on the price they can charge diminishes their power in the marketplace.
The lawsuit will likely go to trial next year.
Wednesday, October 14, 2015
The Hill (Oct. 13, 2015): Planned Parenthood Stops Taking Money for Fetal Tissue Donation, by Sarah Ferris:
Planned Parenthood's president Cecile Richards wrote a letter to the National Institutes of Health stating that the organization will no longer be accepting reimbursement for its fetal tissue donation program.
“This new policy removes beyond the shadow of a doubt the ludicrous idea that Planned Parenthood has any financial interest in tissue donation — and shows the real agenda behind these attacks,” Richards wrote in a statement.
Wednesday, March 4, 2015
The Guardian: Britain's House of Lords approves conception of three person babies, by Hannah Devlin:
Britain has become the first country in the world to permit the use of “three-person IVF” to prevent incurable genetic diseases.
The House of Lords voted by 280 votes to 48 on Tuesday evening to approve changes to the law allowing fertility clinics to carry out mitochondrial donation. Babies conceived through this IVF technique would have biological material from three different people – a mother, father and a female donor. . . .
Technically the baby would have three biological parents, with 99.8% of genetic material coming from the mother and father and 0.2% coming from the mitochondrial donor. . . .
PBS: Why the term 'three-person baby' makes doctors wince, by Rebecca Johnson:
MELAS is one of about 200 known mitochondrial diseases, a subject that has featured prominently in the news since the British Parliament’s House of Commons on Feb. 3 approved further testing and research on mitochondrial replacement IVF. The procedure has beencommonly referred to in news stories as “three-person babies” or “three-parent babies.”
But it’s a term that makes doctors wince. . . .
Friday, March 21, 2014
New technology would enable women who carry harmful mutations in their mitochondria to have a child without those harmful mutations. Despite concerns, that's a good thing.
Since January, a new California law allows for a child to have more than two legal parents. But children are still limited to two genetic parents. That could change soon, if the Food and Drug Administration approves human clinical trials for a technique known as mitochondrial replacement, which would enable a child to inherit DNA from three parents.
News of the pending application has caused a kind of panic not seen since Dolly the sheep was cloned, raising the possibility of a single genetic parent. But far from being the end of the human race as we know it, the technique might be a way to prevent hundreds of mitochondrial-linked diseases, which affect about one in 5,000 people. . . .
Saturday, March 1, 2014
The Los Angeles Times: Study calls DNA test reliable in discovering fetal disorders, by Monte Morin:
The screening more accurately identifies likely cases of genetic disorders caused by extra chromosomes, like Down syndrome, in a study of low-risk pregnant women.
It's billed as a faster, safer and more accurate way of screening expectant mothers for fetal abnormalities like Down syndrome, and proponents say it has already become the standard for prenatal care.
But as a handful of California companies market their DNA-testing services to a growing number of pregnant women, some experts complain that the tests have not been proven effective in the kind of rigorous clinical trials that are required of new drugs.
Now, a study published Wednesday by the prestigious New England Journal of Medicine has verified that one of the tests can identify likely cases of Down syndrome and other genetic disorders caused by extra chromosomes in low-risk women with greater reliability than traditional noninvasive screening methods. . . .
Wednesday, February 26, 2014
USA Today: FDA raises concerns about three-parent embryo procedure, by Karen Weintraub:
In two days of hearings ending Wednesday, a federal committee proved quite skeptical about research that might help some patients birth healthy children — but might also open the door to human gene manipulation.
The procedure being considered, called mitochondrial transfer, would mix the genes of two women in hopes of creating a healthy baby. . . .
WebMD: FDA Explores '3-Person' Embryo Fertilization, by Dennis Thompson:
U.S. Food and Drug Administration hearings opened Tuesday on a controversial fertilization technique that uses the DNA from three people -- two women and one man -- with the goal of preventing inherited genetic diseases. . . .
Wednesday, February 5, 2014
Reuters: Brain-dead Canadian woman kept on life support to save fetus, by Julie Gordon:
A 32-year-old Canadian woman who has been declared brain dead is being kept on life support in a Victoria, British Columbia hospital, with doctors working to keep her alive long enough to deliver her unborn son. . . .
The New York Times: Ethics Questions Arise as Genetic Testing of Embryos Increases, by Gina Kolata:
. . . Genetic testing of embryos has been around for more than a decade, but its use has soared in recent years as methods have improved and more disease-causing genes have been discovered. The in vitro fertilization and testing are expensive — typically about $20,000 — but they make it possible for couples to ensure that their children will not inherit a faulty gene and to avoid the difficult choice of whether to abort a pregnancy if testing of a fetus detects a genetic problem.
But the procedure also raises unsettling ethical questions that trouble advocates for the disabled and have left some doctors struggling with what they should tell their patients. . . .
Friday, September 20, 2013
The Guardian (op-ed): Why women have a right to sex-selective abortion, by Sarah Ditum:
As far as I'm concerned, it doesn't matter why any woman wants to end her pregnancy. If it's to select for sex, that's her choice
When you talk about being pro-choice, sex selective abortion is often slung at you as the triumphant gotcha. "You love women so much you want them to be in charge of what grows inside their bodies, but what about the women who are aborted, have a go at answering that? ZING!"
The answer is actually remarkably simple, and it's this: it doesn't matter whether what's growing inside you is liable to end up as a man or a woman. What matters is whether the person it's growing inside – the person who is going to have to deliver the resulting baby, at not inconsiderable personal peril – actually wants to be pregnant and give birth to this child. . . .
Saturday, August 17, 2013
Pew Research - Religion & Public Life Project: Abortion Viewed in Moral Terms: Fewer See Stem Cell Research and IVF as Moral Issues:
Regardless of their views about the legality of abortion, most Americans think that having an abortion is a moral issue. By contrast, the public is much less likely to see other issues involving human embryos – such as stem cell research or in vitro fertilization – as a matter of morality. . . .
Lifenews seems somewhat puzzled by the discrepancy:
A new Pew research poll finds Americans say abortion is morally wrong by a 3-1 margin. However, Americas are still divided on the issue of embryonic stem cell research — even though it destroys human life and still has not helped any patients. . . .
But perhaps anti-choice groups themselves are partly to blame:
The Atlantic Wire: Americans See Abortion, But Not Stem Cell Research, as a Moral Issue, by Abby Ohl Heiser:
. . . While the issue is currently framed in "momentum" language familiar to any election horse race aficionado, our views on its legalization overall have stayed pretty steady since Roe v. Wade. . . . So what's momentum got to do with it?
For starters, the far-right legislative push to pass a series of abortion-restricting laws is bringing a cornucopia of moral associations with it, ones that resonate with conservative-leaning politics. . . .
For scholarly analysis of this issue, see my articles The Meaning of 'Life': Belief and Reason in the Abortion Debate and Roe v. Wade's 40th Anniversary: A Moment of Truth for the Anti-Abortion-Rights Movement?
Wednesday, August 7, 2013
The New York Times - op-ed: End of Life, at Birth, by April R. Dworetz:
FIFTY years ago this Wednesday, Americans were gripped by the fate of a baby — Patrick Bouvier Kennedy, the first child born to a sitting president since the 19th century, and John F. Kennedy’s last. He arrived on Aug. 7, 1963, five and a half weeks premature. Despite medical heroics, including the use of a hyperbaric oxygen chamber, he died 39 hours later.
Neonatal care has improved greatly since then. Were he born today, Patrick, who was delivered at 34 weeks’ gestation, would very likely survive and have a healthy life, too.
For all the biomedical advances, though, the key ethical problems surrounding premature birth remain. . . .
H/T: Carol Sanger
Monday, July 15, 2013
The Los Angeles Times - op-ed: Leveling the field for human egg donors, by Naomi Cahn & June Carbone:
A bill before Gov. Jerry Brown would make it legal for research programs to pay for human eggs, as they do for sperm. But the issue is complicated.
In the United States, there is a competitive market in human eggs provided for reproductive purposes. An "extraordinary" egg donor can earn as much as $50,000 when she offers her eggs to an infertile couple. In California, however, that same "extraordinary" individual would receive nothing, aside from payment for her direct expenses, if she provided those same eggs for research purposes. That could change soon. . . .
Friday, June 7, 2013
I. Glenn Cohen and Travis G. Coan (both of Harvard Law School) have posted Can You Buy Sperm Donor Identification? An Experiment. Here is the abstract:
In the United States, most sperm donations are anonymous. By contrast, many developed nations require sperm donors to be identified, typically requiring new sperm (and egg) donors to put identifying information into a registry that is made available to a donor-conceived child once they reach the age of 18. Recently, advocates have pressed U.S. states to adopt these registries as well, and state legislatures have indicated openness to the idea. This study re-lies on a self-selected convenience sample to experimentally examine the economic implications of adopting a mandatory sperm donor identification regime in the U.S. Our results support the hypothesis that subjects in the treatment (non-anonymity) condition need to be paid significantly more, on average, to donate their sperm. When restricting our attention to only those subjects that would ever actually consider donating sperm, we find that individuals in the control condition are willing-to-accept an average of $$43 to donate, while individuals in the treatment group are willing-to-accept an aver-age of $74. These estimates suggest that it would cost roughly $31 per sperm donation, at least in our sample, to require donors to be identified. This price differential roughly corresponds to that of a major U.S. sperm bank that operates both an anonymous and identify release programs in terms of what they pay donors.
Wednesday, March 6, 2013
NBC Connecticut: Surrogate Gives Birth Against Biological Family's Wishes, by Josh Chapin:
The couple offered her $10,000 to have an abortion, but she refused.
When a Vernon woman was hired to be a surrogate in 2011, she never expected that the decision would lead to a more agonizing decision about the fate of a little girl, a battle in the courts and a move out of state so she had the power to make choices about the child's welfare. . . .
NBCNEWS.com - Vitals: $10,000 to abort? Surrogacy case reveals moral holes bioethicist says, by Arthur Caplan:
Crystal Kelley got paid $22,000 to have a baby. But that wasn’t the only offer the 29-year-old Connecticut mother of two received. After an utrasound at 21-weeks revealed significant medical issues, the parents offered her $10,000 more if she agreed to an abortion.
The gross immorality of that second offer tells us that there is a lot wrong with the first arrangement. It is intolerable that our society continues to put up with an unregulated, free market in hiring cash-starved women to make babies. . . .
Washington Post - She The People blog: Surrogate mother refused abortion: Right? Wrong? Damned to hell?, by Aly Neel:
A surrogate mother and the couple that hired her make a painful discovery after an ultrasound: Their unborn child will have serious health problems and will possibly never have a “normal” life.
The biological parents, who say they cannot bring a child into the world to endure so much suffering, offer the surrogate, who is struggling to make ends meet, $10,000 to abort the baby. . . .
Monday, March 4, 2013
WNYC - The Brian Lehrer Show: Ask a Bioethicist: Reproductive Technology:
We begin a series about medical ethics with Duke University bioethicist Nita Farahany, who sits on the Presidential Commission for the Study of Bioethical Issues. Each week, she'll discuss some of the thorniest bioethical conundrums of our day.
Today's topic: Reproductive technology. We want your suggestions of bioethical questions we should discuss. Should parents be able to choose the sex of their baby? Should there be age limitations on people who undergo in vitro fertilization? That kind of thing. Ask your question below and we'll tackle as many as we can.
The show airs on Tuesday, March 5. Submit your question here.
Monday, December 10, 2012
Sarthak Garg & Keshav Gaur (both of Rajiv Gandhi National University of Law) have posted Reproduction Rights of Women: Ethical or Viable Role of Surrogate Mother on SSRN. Here is the abstract:
Reproductive behavior is governed by complex biological, cultural and psychological relations, hence reproductive health and rights must be understood within the context of relationships between men and women, communities and societies. This research encompasses with these problems which concerned about the reproductive health and rights of the women. It furthermore explains the vulnerability of women and gender biased violence against them. This paper also laid stress on the impact of men’s action over the reproductive health and rights of the women and the key initiatives to deliver reproductive rights and services to the women. Though, this paper also focuses on the rights of the surrogates’ mother and the initiatives taken by the government for the enhancement of the surrogacy and their rights in India. In this research we conceptualize the incidents related to the surrogacy and the legal issues in the global scenario. However, we also gestate the landscape of surrogacy in India, as it is new concept for India and not acceptable as well on various portfolios so we also laid focus on the social and economic background for the profound this concept in the grass root level. While construing this research we also analysis the Artificial Reproductive Technology (ART) bill, in that we critically analysis it’s positive and negative aspects for the concept of surrogacy in India. Eventually, this research also laid impact over the commissioning parents and their rights regarding surrogacy. In the conclusion our research concludes procreating a child in surrogate woman’ womb is grateful gift to those mothers who cannot conceive child.
Sunday, December 9, 2012
The Province: Battle looms over Tory MP's motion on sex-selective abortion, by Jordan Press:
A Conservative backbencher’s motion on sex-selective abortions caught the ire of opposition parties Wednesday, with the NDP and Liberal leaders claiming it was another attempt to outlaw abortion, while the MP behind the proposal called it a stand for human rights.
The volleys over Tory MP Mark Warawa’s motion are part of an ongoing tug-of-war between anti-abortion MPs who want to claim the motion for their cause, and advocates who want to keep the proposal distanced from the politically controversial abortion debate. . . .
Wednesday, December 5, 2012
Richard F. Storrow (CUNY School of Law) has posted Judicial Review of Restrictions on Gamete Donation in Europe on SSRN. Here is the abstract:
The decision of S.H. and Others v. Austria vindicates the right of governments to enact restrictions on gamete donation against claims that these restrictions violate the guarantees of the European Convention on Human Rights. Van Hoof and Pennings in this issue predict that legal diversity on the question of gamete donation will persist in the wake of this decision and discuss how the decision itself is insufficiently protective of the private and family interests of individuals who seek reproduction-assisting medical treatment. This commentary discusses the difficult balancing work of the European Court of Human Rights, its questionable expansion of the margin appreciation doctrine in S.H. and Others v. Austria and how the decision might influence national courts in the future.