HealthLawProf Blog

Editor: Katharine Van Tassel
Akron Univ. School of Law

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Saturday, November 22, 2008

Rats and TB Detection

Images The Boston Globe's  Colin Dickerson reports on a new use for rats - its turns out that they can help solve some fairly major public health problems.  I know most people probably think of rats as a public health problem but according to this article they have been put to use detecting landmines and TB.  The article is quite interesting and states,

Meanwhile, in a conceptual leap, Weetjens decided to turn the rats' sharp olfactory sense to disease detection, starting with tuberculosis. "The medical applications, I believe, will eventually prove even more important than the hunt for land mines," he predicted.

In the pilot project in the Tanzanian capital of Dar es Salaam and the nearby city of Morogoro, Apopo-trained rats evaluate saliva samples at a rate of 40 every 10 minutes; that's equal to what a skilled lab technician, using a microscope, can effectively complete in a day.

A TB rat signals with unmistakable paw motions when it detects sputum infected by Mycobacterium tuberculosis, the infectious bug responsible for 1.7 million deaths and 9.2 million new TB cases each year, mainly in poor countries, according to the World Health Organization. Scientists at Germany's Max Planck Institute are now trying to determine whether the rats are detecting the scent of the actual TB bacteria or some metabolic reaction produced by the infection.

For both TB and land mines, the rats are trained to respond to the sound of a clicker; when the rat makes the scratching motion that means it has detected an explosive or the odor of disease, the handler or trainer responds by snapping the clicker, which means a nut or fruit is on the way.

So why don't the animals just scratch every few minutes to win a treat? "That would be human behavior," said Weetjens. "Rats are more honest."

I think I will have to re-think my view of rodents.

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