Thursday, March 9, 2006
DuPont scientists published a study recently indicating that inhalation of nanoparticles were not more toxic than larger fine sized particles. DuPont nanoparticle study Other pulmonary toxicology studies demonstrate that nanoparticles administered to the lung are more toxic than larger, fine-sized particles of similar chemistry at identical mass concentrations. As the scientists indicated,
The results described herein provide the first example of nanoscale particle-types which are not more cytotoxic or inflammogenic to the lung compared to larger-sized particles of similar composition. Furthermore, these findings run counter to the postulation that surface area is a major factor associated with the pulmonary toxicity of nanoscale particle-types.